Additional information
| Active substance | Sibutramine | 
|---|---|
| Active Half-Life | 1 hour | 
| Classification | Non-steroidal anorexiant | 
| Dosage | 10-15 mg/day | 
| Acne | No | 
| Water Retention | No | 
| HBR | Perhaps | 
| Hepatotoxicity | Low | 
| Aromatization | No | 
| Lab Test | Blood levels can be measured, though not routinely done | 
| Also known as | Sibutramine hydrochloride monohydrate | 
| Blood pressure | Can increase blood pressure | 
| Trade name | Meridia, Reductil | 
| FORM | Oral | 
| Dosage Unit | Tabs | 
| Reference | SATLSPH11 | 
| Tab Piece | 100 Tabs | 
| Storage conditions | Store at room temperature, keep away from moisture and heat | 
| Chemical name | N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine hydrochloride monohydrate | 
| Formula | C17H26ClNВ·HClВ·H2O | 
| Substance class | Serotonin-norepinephrine reuptake inhibitor (SNRI) | 
| Main action | Reduction in calorie intake by inducing satiety | 
| Half-life | 1.1 hours (sibutramine), 14-16 hours (active metabolites M1 and M2) | 
| Dosage (medical) | Typically 10 mg once daily, may increase to 15 mg if insufficient weight loss | 
| Dosage (sports) | Not recommended for use in sports | 
| Effects | Weight loss, appetite suppression | 
| Side effects | Dry mouth, insomnia, constipation, increased heart rate | 
| Use in sports | Not commonly used due to potential side effects and banned status in many sports | 
| Packing | Bottle | 
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