Additional information
| Active substance | Isotretinoin | 
|---|---|
| Active Half-Life | 20-22 hours | 
| Classification | Dermatotropic drug | 
| Dosage | 20-40 mg/day | 
| Acne | No | 
| Water Retention | No | 
| HBR | No | 
| Hepatotoxicity | Yes | 
| Aromatization | No | 
| Lab Test | Liver function tests, lipid profiles, pregnancy tests | 
| Also known as | 13-cis-Retinoic acid | 
| WAREHOUSE | USA Warehouse 5 | 
| Blood pressure | No significant effect | 
| Trade name | Accutane, Roaccutane, Claravis, others | 
| Storage conditions | Store at controlled room temperature (15-30В°C), protect from light | 
| Chemical name | (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid | 
| Formula | C20H28O2 | 
| Substance class | Retinoid | 
| Main action | Reduces sebum production, corrects abnormal keratinization, has anti-inflammatory properties | 
| Half-life | 10-20 hours | 
| Dosage (medical) | Typically 0.5 to 1 mg per kg of body weight per day, taken in two divided doses | 
| Dosage (sports) | Not applicable | 
| Effects | Reduces acne, decreases sebum production, promotes skin renewal | 
| Side effects | Dry skin, lips and eyes, itching, nosebleeds, muscle aches, sensitivity to sunlight, decreased night vision, potentially severe birth defects if taken during pregnancy | 
| Use in sports | None | 
| Manufacturer | Nakon Medical – US | 
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